Schisanhenol Attenuates OxLDL-Induced Endothelial Dysfunction via an AMPK-Dependent Mechanism,AMERICAN JOURNAL OF CHINESE MEDICINE, vol.51 no.6 pp.1-17 SCI 2023 邱燦宏(Tsan-Hung Chiu)、古昌文(Chang-Wen Ku)、何宗融(Tsung-Jung Ho)、蔡昆霖(Kun-Ling Tsai)、徐瑋璟(Wei-Ching Hsu)、陳佑安(Yu-An Chen)、歐秀中(Hsiu-chung Ou)、陳?儀(CHEN, HSIU-I)*
Schisanhenol ameliorates oxLDL-caused endothelial dysfunction by inhibiting LOX-1 signaling,ENVIRONMENTAL TOXICOLOGY SCI 2023 邱燦宏(Tsan-Hung Chiu)、古昌文(Chang-Wen Ku)、何宗榮(Tsung-Jung Ho)、蔡昆霖(Kun-Ling Tsai)、楊奕彤(Yi-Dung Yang)、歐秀中(Hsiu-chung Ou)*、陳?儀(CHEN, HSIU-I)
Quercetin Mitigates Cisplatin-Induced Oxidative Damage and Apoptosis in Cardiomyocytes through Nrf2/HO-1 Signaling Pathway,AMERICAN JOURNAL OF CHINESE MEDICINE SCI 2022 Wang SH、Tsai KL、Chou WC、Cheng HC、Huang YT、歐秀中(Hsiu-chung Ou)、Chang YC(Chang YC)*
Cordycepin Attenuates Palmitic Acid-Induced Inflammation and Apoptosis of Vascular Endothelial Cells through Mediating PI3K/Akt/eNOS Signaling Pathway,AMERICAN JOURNAL OF CHINESE MEDICINE SCI 2021 古昌文(Ku, Chang-Wen)、何宗融(Ho, Tsung-Jung)、黃志揚(Huang, Chih-Yang)、朱培銘(Chu, Pei-Ming)、歐秀中(Hsiu-chung Ou)、謝佩伶(Hsieh, Pei-Ling)
Low-level laser prevents doxorubicin-induced skeletal muscle atrophy by modulating AMPK/SIRT1/PCG-1α-mediated mitochondrial function, apoptosis and up-regulation of pro-inflammatory responses,Cell and Bioscience SCI 2021 歐秀中(Hsiu-chung Ou)、朱培銘(Chu, Pei-Ming)、Yu?Ting Huang、Hui?Ching Cheng、Wan?Ching Chou、Hsin?Lun Yang、陳?儀(CHEN, HSIU-I)、蔡昆霖(Kun?Ling Tsa)
The molecular mechanisms underlying arecoline-induced cardiac fibrosis in rats,Open Life Sciences SCI 2021 古昌文(Chang-Wen Ku)、Cecilia Hsuan Day、歐秀中(Hsiu-chung Ou)、何宗融(Tsung-Jung Ho)、Ray-Jade Chen、Velmurugan Bharath Kumar,、Wen-Yuan Lin、黃志揚(Huang, Chih-Yang)
Baicalin Enhances Chemosensitivity to Doxorubicin in Breast Cancer Cells via Upregulation of Oxidative Stress-Mediated Mitochondria-Dependent Apoptosis,Antioxidants (Basel) Other 2021 林美儀(Lin, Mei-Yi)、Wan-Ting Cheng、Hui-Ching Cheng、Wan-Ching Chou、陳?儀(Chen, Hsiu-I)、歐秀中(Hsiu-chung Ou)、蔡昆霖*
Epigallocatechin Gallate Reduces Homocysteine-Caused Oxidative Damages through Modulation SIRT1/AMPK Pathway in Endothelial Cells,AMERICAN JOURNAL OF CHINESE MEDICINE SCI 2021 白培英、Wan-Ching Chou、Shih-Hung Chan、Shu-Yih Wu、陳?儀(CHEN, HSIU-I)、李啟文(Li Chi Wen)、Pei-Ling Hsieh、Pei-Ming Chu、Yu-An Chen、歐秀中(Hsiu-chung Ou)*
Protective Effects of Luteolin Against Oxidative Stress and Mitochondrial Dysfunction in Endothelial Cells,NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, vol.30 no.6 pp.1032-1043 SCI 2020 陳?儀(Hsiu-I. Chen)、Wei-Syun Hu、Meng-Yu Hung、歐秀中(Hsiu-chung Ou)、黃素華(Su-Hua Huang)、Pei-Tzu Hsu、Cecilia-Hsuan Day、Kuan-Ho Lin、Vijaya P Viswanadha(Vijaya P Viswanadha)*、郭薇雯(Wei-Wen Kuo)、歐秀中(Hsiu-chung Ou)
Deep Sea Minerals Ameliorate Diabetic-Induced Inflammation via Inhibition of TNFα Signaling Pathways,ENVIRONMENTAL TOXICOLOGY, vol.35 SCI 2020 Lu CH、歐秀中(Hsiu-chung Ou)、Day CH、陳?儀(Chen HI)、白培英(Pai PY)、Lee CY、Chen RJ、Chang RL、Vijaya P. Viswanadha、黃志揚(Huang, Chih-Yang)*、歐秀中(Hsiu-chung Ou)
Neuroprotective Effect of Rhodiola crenulata in D-Galactose-Induced Aging Model,AMERICAN JOURNAL OF CHINESE MEDICINE SCI 2020 Hsiu-I Chen、歐秀中、Chung-Yu Chen、Shao-Hong Y、鄭秀敏(Shiu-Min Cheng)、Xu-Bo Wu、李信達(Shin-Da Lee)
Neuroprotective Effect of Rhodiola crenulata in D-Galactose-Induced Aging Model,The American journal of Chinese medicine, vol.48 no.2 pp.373-390 Other 2020 Hsiu-I Chen、歐秀中(Hsiu-chung Ou)
Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain,The American journal of Chinese medicine, vol.48 no.2 pp.391-406 Other 2020 Shiu-Min Cheng、歐秀中(Hsiu-chung Ou)
Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways to attenuate diabetes-induced hypertrophy in rat hearts.,Journal of applied physiology, vol.127 no.2 pp.356-364 Other 2019 Lu CH(Lu CH)*、Shen CY、Hsieh DJ、Lee CY、Chang RL、Ju DT、白培英(Pai PY)、Viswanadha VP、歐秀中(Ou Hsiu-Chung)、黃志揚(Huang CY)
Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathway,ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY SCI 2019 歐秀中、Wan-Ching Chou、洪菁霞(Ching-Hsia Hung)、朱培銘(Pei-Ming Chu)、謝珮伶(Pei-Ling Hsieh)、Shih-Hung Chan、蔡昆霖(Kun-Ling Tsai)*
Luteolin: a natural flavonoid enhances the longevity of HUVECs against oxidative stress by modulating AMPK/PKC pathway.,The American journal of Chinese medicine, vol.47 no.3 pp.541-557 Other 2019 Pandey S(Pandey S)*
Fucoxanthin Protects against oxLDL-Induced Endothelial Damage via Activating the AMPK-Akt-CREB-PGC1α Pathway,MOLECULAR NUTRITION & FOOD RESEARCH SCI 2019 歐秀中(Ou, Hsiu-Chung)、Wan-Ching Chou、Pei-Ming Chu、Pei-Ling Hsieh、洪菁霞(Ching-Hsia Hung)、蔡昆霖(Kun-Ling Tsai)*
Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells,MOLECULAR NUTRITION & FOOD RESEARCH, vol.62 no.11 pp.e1700928- SCI 2018 蔡昆霖(Tsai, Kun-Ling)、洪菁霞(Hung, Ching-Hsia)、詹世鴻(Chan, Shih-Hung)、謝佩伶(Hsieh, Pei-Ling)、歐秀中(Ou, Hsiu-Chung)、鄭詠馨(Cheng, Yung-Hsin)、朱培銘(Chu, Pei-Ming)*
Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells. Mol Nutr Food Res,IRISH JOURNAL OF AGRICULTURAL AND FOOD RESEARCH, vol.62 no.11 pp.e1700928- SCI 2018 Tsai KL(Tsai KL)*
Viswanadha VP, Kuo WW, Huang CY. Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis. PLoS One.,PLoS One, vol.12 no.6 pp.e0179492- SCI 2017 Wen SY(Wen SY)*
Diallyl trisulfide & diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats.,PHYSICS OF PARTICLES AND NUCLEI, vol.114 no.3 pp.402-410 SCI 2017 Huang YT(Huang YT)*
Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis,PLoS One, vol.12 no.6 pp.e1709492- SCI 2017 Wen SY(Wen SY)*
Eicosapentaenoic acid protects against palmitic acid-induced endothelial dysfunction via activation of the AMPK/eNOS pathway.,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.15 no.6 pp.10334-10349 SCI 2014 Lee CH,(Lee CH,)*
Exercise training enhances cardiac IGFI-R/PI3K/Akt and Bcl-2 family associated pro-survival pathways in streptozotocin-induced diabetic rats,INTERNATIONAL JOURNAL OF CARDIOLOGY, vol.167 no.2 pp.478-485 SCI 2013 Cheng SM(Cheng SM)*
Ginkgo biloba extract attenuates oxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism,PHYSICS OF PARTICLES AND NUCLEI, vol.114 no.2 pp.274-285 SCI 2013 Hsieh YL,(Hsieh YL,)*
Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway,MOLECULAR NUTRITION & FOOD RESEARCH, vol.55 no.2 pp.227-240 SCI 2012 Kun-Ling Tsai(Kun-Ling Tsai)*
A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways.,JOURNAL OF VASCULAR SURGERY, vol.23 no.5 pp.458-468 SCI 2012 Tsai KL(Tsai KL)*
Aspirin inhibits resistin-induced endothelial dysfunction: roles of ROS and Akt/eNOS/NO signaling pathway.,JOURNAL OF VASCULAR SURGERY, vol.55 no.4 pp.1104-1115 SCI 2012 Lee WJ,( Lee WJ,)*
Green tea epigallocatechin-3-gallate (EGCG) reduced endothelial cells dysfunction and adhesion molecule expression induced by oxidized-LDL.,BIOCHEMICAL PHARMACOLOGY, vol.82 no.12 pp.1807-1821 SCI 2011 Tsai KL(Tsai KL)*
Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways.,BIOCHEMICAL PHARMACOLOGY, vol.674 no.2-3 pp.227-233 SCI 2011 Chen JY(Chen JY)*
EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling,EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, vol.108 no.6 pp.1745-1756 SCI 2010 Tsai KL(Tsai KL)*
Protective effects of magnolol against oxidized LDL-induced cytotoxicity in endothelial cells.,JOURNAL OF VASCULAR SURGERY, vol.81 no.6 pp.421-432 SCI 2007 Hsiu-Chung Ou(Hsiu-Chung Ou)*
Resveratrol, a polyphenolic compound in red wine, protects against oxidized LDL-induced cytotoxicity in endothelial cells.,CLINICA CHIMICA ACTA, vol.2006 no.364 pp.196-204 SCI 2006 Hsiu-Chung Ou
Rosiglitazone inhibits endothelial proliferation and angiogenesis.,LIFE SCIENCES, vol.2006 no.364 pp.196-204 SCI 2006 Sheu WH
Hypercholesterolemia, not metabolic syndrome, related to adhesion of monocytes to cultured endothelium in nondiabetic subjects. Metabolism.,METABOLISM-CLINICAL AND EXPERIMENTAL, vol.2005 no.54 pp.1467-1471 SCI 2005 Lee IT
(-)Epigallocatechin-3-gallate (EGCG), a Polyphenolic Compound in Green Tea, Protetcs Against Endothelial Cells Inflammation via Oxidized LDL.,JOURNAL OF CELLULAR BIOCHEMISTRY, vol.96 no.1 pp.183-197 SCI 2005 Chi-Feng Hung(Chi-Feng Hung)*
Solanum Lyratum Thumb Prevent Oxidized Low-density Lipoprotein-induced Endothelial Dysfunction.,Medicine & Science in Sports & Exercise, vol.41 no.5 pp.172- Other 2005 Tsai KL(Tsai KL)*
Protective Effect of -Keto--Methyl-nValeric Acid on BV-2 Microglia under Hypoxia or Oxidative Stress,Annals of the New York Academy of Sciences SCI 2005 Huang HM
alpha-keto-beta-methyl- n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores.,FREE RADICAL BIOLOGY AND MEDICINE, vol.2004 no.37 pp.1779-1789 SCI 2004 Huang HM
Protective effect of nicotinamide on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation.,JOURNAL OF BIOMEDICAL SCIENCE, vol.2004 no.11 pp.472-481 SCI 2004 Shen CC
Apolipoprotein E polymorphism in various dementias in Taiwan Chinese population.,JOURNAL OF NEURAL TRANSMISSION, vol.2002 no.109 pp.1415-21 SCI 2002 Huang HM
Silymarin protects dopaminergic neurons against lipopolysaccharide- induced neurotoxicity by inhibiting microglia activation.,EUROPEAN JOURNAL OF NEUROSCIENCE, vol.2002 no.16 pp.2103-2112 SCI 2002 Mei-Jen Wang
Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neurons.,LIFE SCIENCES, vol.2000 no.66 pp.1879-1892 SCI 2000 Huang HM
Amyloid beta peptide impaired carbachol but not glutamate-mediated phosphoinositide pathways in cultured rat cortical neurons,CHINESE MEDICAL JOURNAL, vol.2000 no.25 pp.303-312 SCI 2000 Huang HM
Differential alteration of catecholamine release during chemical hypoxia is correlated with cell toxicity and is blocked by protein kinase C inhibitors in PC12 cells.,JOURNAL OF CELLULAR BIOCHEMISTRY, vol.2000 no.79 pp.191-201 SCI 2000 Kuo JS
- Eighth Annual Scientific Sessions: Metabolic Signaling in the Cardiovascular System Alberta, Canada 2010.08 歐秀中(Hsiu-chung Ou)
利用活化抗老化基因保護化療藥物Cisplatin所造成的肌肉受傷 (ASIA-111-CMUH-02) 2022.11.01 ~ 2023.10.31 歐秀中(Hsiu-chung Ou)、邱燦宏、楊奕彤(Yi-Dung Yang)
低能量電射改善化療藥物造成肌肉衰弱之效果探討:從分子機轉到動物研究 (109-2635-B-468-001) 2020.08.01 ~ 2021.07.31 歐秀中(Hsiu-chung Ou)、蔡昆霖(Kun-Ling Tsai)
探討氧化壓力下抗老化基因與Galetin-3交互作用保護內皮細胞凋亡與力腺體功能異常之機轉 (ASIA-108-CMUH-07) 2019.11.01 ~ 2020.10.31 歐秀中(Hsiu-chung Ou)、白培英(Pei-Ying Pai)、吳書毅(Shu-Yih Wu)
Effects of polyphenolic compounds and exercise preconditioning protect against injury in a cerebral ischemia/reperfusion model in rat 2008.08.01 ~ 2009.07.31
Protective effect of sesamin on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation 2007.08.01 ~ 2008.07.31
Effects of ginkgo on oxLDL-promoted interaction between monocyte and vascular endothelium: regulation of redox status, adhesion molecules, and trans-endothelial migration (National Science Council) 2006.08.01 ~ 2007.07.31
神經物理治療實習 (二) TR300104A (大學日間部 )【第111學年第2學期:A班】<br>了解中樞神經系統的結構與功能,經學習或受損之後可產生的神經可塑性,臨床上常見的神經系統疾病,如何透過物理治療增加患者動作功能,恢復日常生活獨立性
特殊族群運動治療 TR300090A (大學日間部 )【第111學年第2學期:A班】<br>本課程旨在針對長照領域常見之特殊群體健康促進議題,進行相關議題之討論。其授課內容之特殊群體包括慢性疾病患者、癌症患者、身心障礙者、孕婦及其它具有特殊需求者。授課內容包含各種特殊群體之需求評估、相關研究文獻導讀、各種特殊群體健康促進模式的建立方法的優缺點及適用性比較。
神經物理治療總論 TR300046A (大學日間部 )【第111學年第2學期:A班】<br>了解中樞神經系統的結構與功能,經學習或受損之後可產生的神經可塑性,臨床上常見的神經系統疾病,如何透過物理治療增加患者動作功能,恢復日常生活獨立性
神經物理治療學(二) TR300035A (大學日間部 )【第111學年第2學期:A班】<br>了解中樞神經系統的結構與功能,經學習或受損之後可產生的神經可塑性,臨床上常見的神經系統疾病,如何透過物理治療增加患者動作功能,恢復日常生活獨立性
基礎物理治療學實習(二) TR300025A (大學日間部 )【第111學年第2學期:A班】<br>1.使學生熟悉基本物理治療評估技巧 2.學習簡易物理治療技巧 3.使學生了解基本運動治療原則與注意事項
生理學 TR300012A (大學日間部 )【第111學年第2學期:A班】<br>使學生理解人體內各種組成層次的功能及各組成層次如何相互協調以維持生理機能的恆定,並使學生能將基礎的生理學知識連結到臨床上的應用;以期藉由對生理學的瞭解,奠定日後從事生物醫學相關領域的研究基礎。